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Published Papers

SUBJECT

CS - AI / ML / Data Science / Quantum Computing / Blockchain / Computer Vision

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Scientific Journal

IJSR - International Journal of Scientific Research

Name of Scholar

Arkoneil Ghosh

Topic

AI-Driven Classification of Alzheimer’s and Parkinson’s Disease Using Phonetic Speech Patterns

About the Scholar

Arkoneil is a student at Oberoi International School, Mumbai, India.

Name of Mentor

Damianos Michaelides

PhD in Statistics - University of Southampton

BSc, (Hons) in Mathematics, Operational Research, Statistics, Economics (MORSE) - University of Southampton

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Summary

Neurodegenerative disorders such as Alzheimer’s and Parkinson’s are challenging to detect early due to their gradual onset. This study investigates the use of machine learning algorithms to identify these conditions based on phonetic features in speech. By analyzing vocal attributes, such as fluency, articulation, and acoustic variation; this research aims to establish non-invasive diagnostic models. Principal Component Analysis (PCA) was used for feature selection, while Random Forest and Support Vector Machine (SVM) classifiers were deployed for detection accuracy. Results show promising accuracy levels, particularly in the Alzheimer’s model, highlighting the potential of AI in enhancing early clinical screening for cognitive decline. 

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SUBJECT

Psychology - Neuroscience / Developmental / Cognitive / Learning & Memory

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Scientific Journal

IJCMPH - International Journal of Community Medicine and Public Health

Name of Scholar

Armeya Dongre

Topic

The role of 40 Hz auditory stimulation in sustaining cognitive health: a pilot study in dementia

About the Scholar

Armeya is a student at Apeejay High School, Navi Mumbai, Maharashtra, India.

Name of Mentor

Emily Beswick

PhD in Psychology - University of Edinburgh

BA (Hons)  in Psychology - University of Edinburgh

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Summary

This case series examined the potential cognitive and neuro-physiological effects of daily auditory stimulation at a 40 Hz gamma frequency with dementia patients. In total, twenty older adults, ages 65–84 years and clinically diagnosed with mild to moderate dementia, completed a structural auditory stimulation procedure lasting for 15 minutes per day for 30 consecutive days. Assessments of cognition were completed using the standardized Mini-Cog test, and resulting neural responses  were quantitatively examined  with electroencephalography (EEG), focusing on gamma-band oscillatory activity. The results demonstrated 40% of participants showed statistically relevant improvements over pre stimulation Mini-Cog scores, demonstrating improvements in memory, attention, and executive functioning.

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SUBJECT

CS - AI / ML / Data Science / Quantum Computing / Blockchain / Computer Vision

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Scientific Journal

IRJMETS - International  Research Journal  of  Modernization in Engineering Technology  and  Science

Name of Scholar

Arnav Rayaprolu

Topic

An Empirical Assessment Of Pairs Trading Using Ensemble Qlearning

About the Scholar

Arnav is a student at Oberoi International School, Mumbai, Maharashtra, India. 

Name of Mentor

Dr. Martin Sewell

PhD in Machine Learning/Financial Markets - University of Cambridge

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Summary

The relentless pursuit of alpha has driven the creation of several quantitative trading strategies, including pairs trading. The recent emergence of reinforcement learning frameworks, such as Q-learning, has led to the development of advanced statistical arbitrage models. This study presents an empirical investigation into the application of ensemble Q- learning, a reinforcement learning method, to pairs trading in the Indian equity market. Utilising hourly data from the NIFTY 50 index constituents, which covers over 128,400 data points, a novel composite scoring framework was devised to select optimal asset pairs, balancing both long-term cointegration and mean-reversion criteria. A custom trading environment was constructed using OpenAI’s gym library to realistically simulate capital constraints, transaction costs, and position management. The agent maintained multiple independently trained Q-tables, aggregating their estimates to reduce variance and improve stability in trading decisions. Hyperparameters for the agent were optimised via a Bayesian search, and strategy performance was evaluated on out-of-sample data across multiple independent runs. Results demonstrate that the ensemble Q-learning agent delivered an average six-month portfolio return of 105.2% with a Sharpe ratio of 2.08, substantially outperforming both traditional pairs trading benchmarks and major global indices. These findings provide rigorous evidence that reinforcement learning, when coupled with well-designed pairs trading strategies, can drive superior alpha generation in financial markets. 

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SUBJECT

Biology - Genetics / Health Studies / Microbiology / Environmental Science

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Scientific Journal

IRJMETS - International  Research Journal of Modernization in Engineering Technology  and  Science

Name of Scholar

Divaa Uthkarsha

Topic

Testing Environmental Modulation Of The Enzyme Catalase As A Framework For Nano-Catalase Therapies In Oxidative Stress-driven Diabetes

About the Scholar

Divaa is a student at National Academy For Learning, Bangalore, Karnataka, India.

Name of Mentor

Guided Research

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Summary

This research paper aims to investigate the activity of the catalase enzyme under varying environmental conditions, including pH value, glucose concentration, and temperature. Catalase is a crucial antioxidant enzyme that breaks down hydrogen peroxide (H₂O₂), a highly reactive oxygen species (ROS), into water and oxygen. In diabetic cells, activities like glycation can impair catalase activity. This stimulates how hyperglycemia in diabetes reduces catalase efficiency. We hypothesize that high glucose and extreme pH or temperature will lower enzyme activity and produce less O₂ gas. Our experiment involves Solanum tuberosum (potato) derived catalase extract, observing its reactions with H₂O₂ and measuring O₂ evolution as an indicator for catalase activity through biological assays under varying environments. The results showed the expected trends: maximum activity at neutral pH and moderate temperature, and reduced activity with high glucose (mimicking diabetic glycation of catalase). 

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SUBJECT

CS - AI / ML / Data Science / Quantum Computing / Blockchain / Computer Vision

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Scientific Journal

IRJMETS - International  Research Journal of Modernization  in Engineering Technology and Science 

Name of Scholar

Shrikruthi Vedula

Topic

AI Chatbots and Therapy: Can AI Chatbots Replace Human Therapists?

About the Scholar

Shrikruthi is a student at Manthan School, Hyderabad, Telangana, India.

Name of Mentor

Dr. Martin Sewell

PhD in machine learning/financial markets, University College London

Postdoctoral Member, University of Cambridge

MSc. in Computer Science, University of London

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Summary

This paper reviews literature where AI chatbots have been experimented with in psychotherapy. In 2015, nearly half the  population lived in countries with fewer than one psychiatrist per 100,000 people. Considering the global shortage, AI chatbots may provide more economic and accessible solutions, though they struggle to replicate the values of human therapists. A conversational AI chatbot can strengthen the therapeutic bond. However, they cannot imitate the emotional depth of a therapist. Of the three dimensions of empathy— cognitive, emotional, and motivational—AI chatbots currently lack two (emotional and motivational). Statistically, chatbots are more effective at reducing symptoms of certain mental conditions, but discontinued use causes a relapse, which is also possible with therapists. Qualitatively, there are mixed opinions on which is better. Overall, all the studies agree that chatbots lack the human touch and sensitivity required to deal with emotions. 

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SUBJECT

Biology - Genetics / Health Studies / Microbiology / Environmental Science

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Scientific Journal

IRJMETS - International Research Journal of Modernization in Engineering Technology and Science

Name of Scholar

Aarush Raju

Topic

The Impacts of Creatine Monohydrate on Athletic Performance and Development

About the Scholar

Aarush is a student at Portola High School, Irvine, CA, USA.

Name of Mentor

Dr. Minerva Singh

MPhil in Geography and Environment - University of Oxford

PhD in Tropical Ecology and Conservation - University of Cambridge

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Summary

Creatine monohydrate is one of the most widely researched and utilized supplements in the fitness industry, known for its role in enhancing athletic performance, muscle growth, and recovery. Naturally obtained through dietary sources such as red meat and seafood, as well as being produced by the liver, creatine plays a critical role in adenosine triphosphate (ATP) regeneration, providing energy for high intensity exercise. This paper explores the physical impacts of creatine supplementation, its benefits in resistance training, and potential reasons to not supplement creatine into one’s diet. A review of existing literature indicates that consistent creatine intake, paired with structured training, leads to increased muscular strength, enhanced training capacity, and reduced injury risk due to improved hydration and muscle integrity. However, some studies present conflicting evidence, suggesting minimal performance enhancement in certain exercises, while others raise concerns about potential adverse effects, particularly for individuals with renal complications. This paper synthesizes these findings to provide a comprehensive evaluation of creatine monohydrate's impact on athletic performance and overall muscle health

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